Peer-Reviewed Journal Details
Mandatory Fields
Dolan, N;McGinley, J;Stephens, JC;Kavanagh, K;Hurley, D;Maher, NJ
2014
January
Inorganica Chimica Acta
Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives
Published
5 ()
Optional Fields
RAY CRYSTAL-STRUCTURES X-RAY IN-VITRO SPECTROSCOPIC CHARACTERIZATION BIOLOGICAL-ACTIVITY ANTITUMOR-ACTIVITY CELL-LINES COPPER(II) ACID MOSSBAUER
409
276
284
The synthesis of several diorganotin(IV) dicarboxylate compounds, including acetates and nicotinates as well as diorganotin(IV) dichloride complexes of the ligands phen, dione and dppz were undertaken. Several difficulties in either the syntheses or complexation reactions with the organic ligands were encountered. The diorganotin(IV) dichloride complexes of the ligands (R2SnCl2 center dot L where R = Me, n-Bu or Ph and L = phen, dione or dppz) were tested against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The dibutyltin(IV) derivatives exhibited the broadest range of activity in comparison to the dimethyltin(IV) or diphenyltin(IV) derivatives. The addition of the nicotinate group did not promote activity against any of the bacteria. Furthermore, only in the case of Ph2SnCl2 center dot dione was there improved activity compared to the organic ligand itself. (C) 2013 Elsevier B.V. All rights reserved.
LAUSANNE
0020-1693
10.1016/j.ica.2013.09.038
Grant Details