Peer-Reviewed Journal Details
Mandatory Fields
Singh, I;Vyle, JS;Heaney, F
2009
January
Chemical Communications
Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation
Published
53 ()
Optional Fields
RUTHENIUM-CATALYZED CYCLOADDITION NITRILE OXIDES IN-VIVO DNA AZIDES ISOXAZOLE ALKYNES REPLACEMENT NUCLEOSIDES REACTIVITY
3276
3278
Solid-phase oligonucleotide conjugation by nitrile oxide-alkyne click cycloaddition chemistry has been successfully demonstrated; the reaction, compatible with all nucleobases, requires no metal catalyst and proceeds under physiological conditions.
CAMBRIDGE
1359-7345
10.1039/b904185k
Grant Details