Peer-Reviewed Journal Details
Mandatory Fields
Beaumont, AJ;Kiely, C;Rooney, AD
2001
March
Journal of Fluorine Chemistry
Synthesis of novel chiral quaternary phosphonium fluorides: reagents for simple asymmetric nucleophilic fluorination reactions
Published
11 ()
Optional Fields
108
47
50
The novel chiral quaternary salt (R-P)-benzylmenthylmethylphenylphosphonium fluoride was synthesised. The compound was used in the asymmetric nucleophilic fluorination of 2-bromopropiophenone to give 7-fluoropropiophenone in a 35% yield with [alpha](D)(20) = +1.94 degrees. (C) 2001 Elsevier Science B.V. All rights reserved.
LAUSANNE
0022-1139
Grant Details