Peer-Reviewed Journal Details
Mandatory Fields
Gavin D.;Stephens J.
2013
July
Arkivoc
Selective Michael additions to alkylidenemalonates using thiourea-based Bifunctional organocatalysts
Published
()
Optional Fields
Alkylidenemalonates Bifunctional thiourea catalysts Michael addition Nitromethane Organocatalysis β-diketones
2013
4
76
87
Bifunctional thiourea catalysts have been found to be excellent promoters of the challenging Michael addition to alkylidenemalonates giving high yields of up to 99%. Substrate structure was important for enantiodiscrimination, with aryl alkylidenemalonate acceptors furnishing products with ee values of up to 73%. ©ARKAT-USA, Inc.
1551-7012
Grant Details