Peer-Reviewed Journal Details
Mandatory Fields
Shevlin, M;McElroy, E;Christoffersen, MN;Elklit, A;Hyland, P;Murphy, J
2016
June
Psychosis
Social, familial and psychological risk factors for psychosis: A birth cohort study using the Danish Registry System
Published
0 ()
Optional Fields
SCHIZOPHRENIA-SPECTRUM DISORDERS GENOME-WIDE ASSOCIATION POPULATION-BASED COHORT CHILDHOOD SEXUAL-ABUSE ADVANCED PATERNAL AGE BIPOLAR DISORDER METAANALYSIS ENVIRONMENT TRAUMA PSYCHOPATHOLOGY
8
95
105
A broad range of biological, genetic, environmental, and psychological risk factors for psychosis have been reported. Large-scale cohort studies using registry data are a reliable means of measuring the impact of these risk factors; however, previous studies employing this methodology have focused on a narrow range of variables. The aim of this study was to use data from a large birth cohort to examine the associations between ICD-10 psychotic diagnosis and a broad range of familial factors (advanced paternal age, family dissolution, parental psychosis), environmental factors (urbanicity, deprivation), psychological factors (childhood adversity) and gender. Data came from the Danish Civil Registration System and the Danish Psychiatric Central Register (N = 54,458). Multivariate binary logistic regression analysis indicated that five of the seven risk factors conferred unique risk for psychosis, with familial history and childhood adversity having the strongest effects. Overall, these findings indicate that familial, environmental and psychological risk factors confer unique risk for psychotic disorder.
ABINGDON
1752-2439
10.1080/17522439.2015.1113306
Grant Details