Peer-Reviewed Journal Details
Mandatory Fields
Fredj, Z;Ben Ali, M;Abbas, MN;Dempsey, E
2020
August
Analytical Methods
Simultaneous determination of ascorbic acid, uric acid and dopamine using silver nanoparticles and copper monoamino-phthalocyanine functionalised acrylate polymer
Published
1 ()
Optional Fields
SURFACE-ENHANCED RAMAN SIMULTANEOUS ELECTROCHEMICAL DETERMINATION OPTICAL-PROPERTIES CARBON NANOTUBES ELECTRODE BEHAVIOR SENSOR FILMS
12
3883
3891
A silver nanoparticle and copper monoamino-phthalocyanine-acrylate (Cu-MAPA) polymer modified glassy carbon electrode was developed for the simultaneous detection of dopamine (DOP), ascorbic acid (AA) and uric acid (UA) using voltammetric techniques. Silver nanoparticles (AgNPs) were synthesised according to the citrate reduction method. Following synthesis and characterisation the copper phthalocyanine polymer was co-deposited with AgNPs realising a surface with enhanced electron transfer which lowered the overpotential required for analyte electro-oxidation. Differential pulse voltammetry (DPV) was employed for the simultaneous determination of dopamine (DOP), ascorbic acid (AA) and uric acid (UA) at AgNP/Cu-MAPA modified surfaces at ca.181 mV and 168 mV respectively. The chemical sensor was also capable of individual quantitation of DOP, UA and AA with detection limits of 0.7, 2.5 and 5.0 nM respectively. Overall, the approach realised a simple and effective electrode modifier for the selective discrimination and quantitation of DOP in the presence of physiological levels of AA and UA.
CAMBRIDGE
1759-9660
10.1039/d0ay01183e
Grant Details