Peer-Reviewed Journal Details
Mandatory Fields
Murphy, J;Shevlin, M;Arseneault, L;Bentall, R;Caspi, A;Danese, A;Hyland, P;Moffitt, TE;Fisher, HL
2021
January
Development and Psychopathology
Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences
Published
0 ()
Optional Fields
AUDITORY-HALLUCINATIONS PERSECUTORY DELUSIONS SELF-HARM COMMAND HALLUCINATIONS MODEL-SELECTION LIFE-HISTORY SCHIZOPHRENIA RISK DEPRESSION SYMPTOMS
A recent suicidal drive hypothesis posits that psychotic experiences (PEs) may serve to externalize internally generated and self-directed threat (i.e., self-injurious/suicidal behavior [SIB]) in order to optimize survival; however, it must first be demonstrated that such internal threat can both precede and inform PEs. The current study conducted the first known bidirectional analysis of SIB and PEs to test whether SIB could be considered as a plausible antecedent for PEs. Prospective data were utilized from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative birth cohort of 2232 twins, that captured SIB (any self-harm or suicidal attempt) and PEs at ages 12 and 18 years. Cross-lagged panel models demonstrated that the association between SIB at age 12 and PEs at age 18 was as strong as the association between PEs at age 12 and SIB at age 18. Indeed, the best representation of the data was a model where these paths were constrained to be equal (OR = 2.48, 95% CI = 1.63-3.79). Clinical interview case notes for those who reported both SIB and PEs at age 18, revealed that PEs were explicitly characterized by SIB/threat/death-related content for 39% of cases. These findings justify further investigation of the suicidal drive hypothesis.
NEW YORK
0954-5794
10.1017/S0954579420001728
Grant Details